Human COL1A1 Protein, Recombinant
产品货号：PR01108HuP1
$ 询价
规格 100ug
产品名称：Human COL1A1 Protein, Recombinant
纯度：≥95 % as determined by SDS-PAGE
内毒素：/
生物活性：/
序列起止：Gln23~Pro161
标签：C-His tag
Uniprot链接：P02452
表达系统：E.coli
种属：Human
预测 N 端：Met
预测分子量：16.16
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件：Store for up to one year at -20°C to -80°C as lyophilized powder.
复溶：Please refer to COA for detailed information
质量验证图：/
别称：Alpha-1 type I collagen
背景信息：Background: Collagen I alpha 1. Type I collagen is the most abundant structural protein of connective tissues such as skin, bone and tendon. It is synthesized as a procollagen molecule which is characterized by a 300 nm triple helical domain flanked by globular N- and C-terminal propeptides (1). The triple helical domain contains Gly-Xaa-Yaa triplets where Xaa and Yaa are frequently proline and hydroxyproline, respectively. The non-helical propeptides are removed by procollagen N- and C-proteinase activities so that the mature triple helices can self-assemble into collagen fibrils that provide tensile strength to tissues (1). Type I collagen is a heterotrimer that consists of two alpha 1(I) chains and one alpha 2(I) chain, although homotrimers consisting of three identical alpha 1(I) chains have also been described (2). This recombinant mini pro-alpha 1(I) collagen consists of a shortened alpha 1(I) chain with following domain structure from N- to C-terminus: N-propeptide, N‑telopeptide, the 33 most N-terminal Gly-Xaa-Yaa repeats, the 33 most C-terminal Gly-Xaa-Yaa repeats, C-telopeptide and C-propeptide. The preparation contains a mixture of the full-length molecule, pN collagen I( alpha 1) and the C-terminal propeptide. This truncated pro-alpha 1(I) collagen is a substrate for procollagen N-proteinase and procollagen C-proteinase.
全称：Collagen alpha-1(I) chain (COL1A1)
说明书：待上传