Human IL22 Protein, Recombinant
产品货号：PR00512HuM1
$ 询价
规格 100ug
产品名称：Human IL22 Protein, Recombinant
纯度：≥95 % as determined by SDS-PAGE
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
生物活性：/
序列起止：Ala34-Ile179
标签：N-His tag
Uniprot链接：Q9GZX6
表达系统：293F/CHOS
种属：Human
预测 N 端：Met
预测分子量：16.06
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件：Store for up to one year at -20°C to -80°C as lyophilized powder.
复溶：Please refer to COA for detailed information
质量验证图：/
别称：ILTIF/ZCYTO18
背景信息：Background: IL-22. Interleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Human IL-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with mouse IL-22 and human IL-10, respectively. The human IL-22 gene is localized to chromosome 12q15. Although it exists as a single copy gene in human and in many mouse strains, the mouse IL-22 gene is duplicated in some mouse strains including C57B1/6, FVB and 129. The two mouse genes designated IL-TIF alpha and IL-TIF beta, share greater than 98% sequence homology in their coding region. IL-22 has been shown to activate STAT‑1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.
全称：Interleukin-22 (IL22)
说明书：待上传