Human TGFb1 Protein, Recombinant


产品货号:PR00047HuM1
   
询价

规格    100ug

产品名称Human TGFb1 Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素< 1.0 EU per μg of the protein as determined by the LAL method
 
生物活性/
 
序列起止Ala279-Ser390
 
标签N-His tag
 
Uniprot链接P01137
 
表达系统293F
 
种属Human
 
预测 N 端Met
 
预测分子量12.32
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Store for up to one year at -20°C to -80°C as lyophilized powder.
 
复溶Please refer to COA for detailed information
 
质量验证图:/

别称LAP/TGFB
 
背景信息TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).

全称Transforming growth factor beta-1 proprotein (TGFB1)

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