Human FABP3 Protein, Recombinant

产品货号：PR00313HuP1
   
$ 询价

规格    100ug

产品名称：Human FABP3 Protein, Recombinant
 
纯度：≥95 % as determined by SDS-PAGE
 
内毒素：/
 
生物活性：/
 
序列起止：Val2~Ala133
 
标签：C-His tag
 
Uniprot链接：P05413
 
表达系统：E.coli
 
种属：Human
 
预测 N 端：Met
 
预测分子量：14.52 kDa
 
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件：Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶：Please refer to COA for detailed information
 
质量验证图：/

别称：MDGI, FABP11, H-FABP, O-FABP, Hfabp, FABP3, Fatty Acid Binding Protein 3, Muscle And Heart, Mammary Derived Growth Inhibitor, Fatty Acid Binding Protein 11, Muscle fatty acid-binding protein, Heart-ty
 
背景信息：FABP3/H-FABP. Fattyacid binding protein-3 (FABP3; also named Fatty acid binding protein 11,FABP11, H- or M- (heart or muscle) FABP, Mammary derived growth inhibitor, orMDGI) is a member of a large superfamily of lipid binding proteins that areexpressed in a tissue specific manner (1, 9, 10). FABP3 is one of tencytoplasmic FABPs that are 14-15 kDa in size and range from 126-140 aminoacids (aa) in length (1,  2, 3). Although all are highly conserved in theirtertiary structure, there is only modest aa identity between any two members.The FABP family members are subdivided based on organ or tissue type it wasoriginally expressed or identified; liver- (L-FABP), intestine- (I-FABP), heart-(H-FABP), adipocyte- (A-FABP), epidermal- (E-FABP), ileal- (IL-FABP), brain-(B-FABP), myelin- (M-FABP) and testis-FABP (T-FABP) (1). Human H-FABP, the productof the FABP3 gene, is a 132 aa cytosolic protein that shows a flattened beta-barrel structure generated by a series of antiparallel beta ‑strands and twoalpha ‑helices(4, 5, 7). One molecule of FABP3 is capable of binding onelong-chain fatty acid (6, 8, 11).It is suggested that ligands first bind to the outside of the molecule, andthis binding subsequently induces a conformational change in the bindingprotein, resulting in "internalization" of the ligand (7, 11). HumanFABP3 is 86%, 89% and 89% aa identical to mouse, rat and canine FABP3,respectively. It also shows 29% and 32% aa identity to human L-FABP and I‑FABP, respectively.

全称：Fatty acid-binding protein, heart (FABP3)

说明书：待上传