Human ABCB1 Protein, Recombinant


产品货号:PR00337HuP1
   
询价

规格    100ug

产品名称Human ABCB1 Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Thr1023~Gln1280
 
标签C-His tag
 
Uniprot链接P08183
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量28.38 kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
质量验证图:/

别称CD243, ABCB1, ABC20, CLCS, GP170, MDR1, PGY1, P-Glycoprotein, Multidrug resistance protein 1, ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1, Colchicin Sensitivity
 
背景信息ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer. For optimal WB detection with 22336-1-AP, we recommend to avoid boiling the sample after lysis.

全称ATP-dependent translocase ABCB1 (ABCB1)

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