Human SMAD4 Protein, Recombinant

产品货号:PR00469HuP1
   
询价

规格:100ug

产品名称Human SMAD4 Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Trp323~Asp552
 
标签C-His tag
 
Uniprot链接Q13485
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量20.3kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
别称DPC4, JIP, MADH4, Deletion target in pancreatic carcinoma 4
 
背景信息Mammalian homologs of the Drosophila Mad gene include Smad1, Smad2, Smad3, Smad4 (DPC4), Smad5, Smad6, Smad7 and Smad8.  Smad1 and Smad5 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF  and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members . Smad6 and Smad7 regulate the response to activin/ TGF  signaling by interfering with TGF -mediated phosphorylation of other Smad family members. 

全称Mothers against decapentaplegic homolog 4 (SMAD4)
 
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