Human IGF1R Protein, Recombinant

产品货号:PR00508HuP1
   
询价

规格:100ug

产品名称Human IGF1R Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Asp741~His935
 
标签C-His tag
 
Uniprot链接P08069
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量21.45 kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
别称CD221, IGF1-R, IGFIR, JTK13
 
背景信息IGF-I R/IGF1R. IGF-I receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two  alpha  and two  beta  subunits. Both the  alpha  and  beta  subunits are encoded within a single receptor precursor cDNA. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The  alpha  subunit of IGF-I receptor is extracellular while the  beta  subunit has an extracellular domain, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The IGF-I receptor is highly expressed in all cell types and tissues. Essentially all of the biological activities of IGF-I and II have been shown to be mediated via IGF-I R.
 
全称Insulin-like growth factor 1 receptor (IGF1R)
 
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