Human PPBP Protein, Recombinant

产品货号:PR00524HuP1
   
询价

规格:100ug

产品名称Human PPBP Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Ser35~Asp128
 
标签C-His tag
 
Uniprot链接P02775
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量10.34 kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
别称CXCL7, PPBP, PBP, B-TG1, CTAP-III, CTAP3, CTAPIII, LA-PF4, LDGF, MDGF, NAP2, SCYB7, TC1, TC2, TGB1, THBGB1, Pro-Platelet Basic Protein, Beta-Thromboglobulin
 
背景信息CXCL7/NAP-2. Neutrophil Activating Peptide 2 (NAP-2), Connective Tissue Activating Protein III (CTAP-III) and  beta -thrombogulin ( beta -TG), are proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR2 and to chemoattract and activate neutrophils. Although CTAP-III,  beta -TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. It has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity.
 
全称Platelet basic protein (PPBP)
 
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