Human TAB2 Protein, Recombinant

产品货号:PR00562HuP2
   
询价

规格:100ug

产品名称Human TAB2 Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Tyr532~Phe693
 
标签N-terminal GST tag
 
Uniprot链接Q9NYJ8
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量43.82KDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
别称KIAA0733, MAP3K7IP2
 
背景信息Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].
 
全称TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (TAB2)
 
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