Human CCL26 Protein, Recombinant
产品货号:PR00836HuP1
$ 询价
规格:100ug
产品名称:Human CCL26 Protein, Recombinant
纯度:≥95 % as determined by SDS-PAGE
内毒素:/
生物活性:/
序列起止:Ser27~Leu94
标签:C-His tag
Uniprot链接:Q9Y258
表达系统:E.coli
种属:Human
预测 N 端:Met
预测分子量:/
缓冲液:20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式:This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件:Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
复溶:Please refer to COA for detailed information
别称:CCL26, SCYA26, IMAC, TSC-1, Eotaxin 3, Thymic stroma chemokine-1, Chemokine(C-C-Motif)ligand 26, Thymic Stroma Chemokine-1, Small Inducible Cytokine Subfamily A 26
背景信息:CCL26/Eotaxin-3. Eotaxin-3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3/CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin-3/CCL26 expression can also be detected in various tissues. The expression of Eotaxin-3/CCL26 in vascular endothelial cells has been shown to be up-regulated by IL-13 and IL-4.Eotaxin-3/CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. RecombinantEotaxin-3/CCL26 has been produced in insect cells using a baculovirus expression system and shown to contain 71 aa residues. RecombinantEotaxin-3/CCL26 is chemotactic for eosinophils and PHA-activated T cells. Eotaxin-3/CCL26 induces calcium flux in eosinophils as well as in CCR3-transfected cells. Eotaxin-3/CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands. Both the 71 aa residue and 68 aa residue variants of recombinant Eotaxin-3 have been expressed in E. coli and found to have equal potency in inducing chemotaxis of a human CCR3-transfected cell line.
全称:C-C motif chemokine 26 (CCL26)
说明书:待上传