Human PPIA Protein, Recombinant
产品货号:PR00941HuP1
$ 询价
规格:100ug
产品名称:Human PPIA Protein, Recombinant
纯度:≥95 % as determined by SDS-PAGE
内毒素:/
生物活性:/
序列起止:Val2~Glu165
标签:C-His tag
Uniprot链接:P62937
表达系统:E.coli
种属:Human
预测 N 端:Met
预测分子量:17.88KDa
缓冲液:20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式:This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件:Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
复溶:Please refer to COA for detailed information
别称:PPIA, CyP-A, CYPH, Peptidylprolyl Isomerase A, Peptidyl-Prolyl Isomerase A, Peptidyl-prolyl cis-trans isomerase A, Cyclosporin A-binding protein
背景信息:Cyclophilin A. Cyclophilin A, also called Peptidyl-prolyl Isomerase A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis- and trans- proline residues critical for proper folding of proteins (1). Cyclophilin is also incorporated into many viruses, including HIV-1, where it has been speculated to be involved in functions such as viral assembly and infectivity (2). The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity (3) and prevent incorporation of cyclophilin into viral particles (4). The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin (3, 5), making it a useful inhibitor for studying calcineurin activity.
全称:Peptidyl-prolyl cis-trans isomerase A (PPIA)
说明书:待上传