Human HSP90AA1 Protein, Recombinant
产品货号：PR01006HuP1
$ 询价
规格 100ug
产品名称：Human HSP90AA1 Protein, Recombinant
纯度：≥95 % as determined by SDS-PAGE
内毒素：/
生物活性：/
序列起止：Pro2~Asp732
标签：C-His tag
Uniprot链接：P07900
表达系统：E.coli
种属：Human
预测 N 端：Met
预测分子量：/
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件：Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
复溶：Please refer to COA for detailed information
质量验证图：/
别称：HSP90A/HSPC1/HSPCA/HSP 86/HSP86/LAP-2/LPS-associated protein 2/
背景信息：HSP90 alpha. Members of the HSP90 family are essential chaperones found in all organisms from bacteria to humans. HSP90 complexes often interact with proteins in their native conformation and help to maintain/stabilize ligand-bound states. In this capacity, HSP90 plays a central role in function and turnover of many proteins involved in processes such as signal transduction, cell cycle control and apoptosis. HSP70 family members and HSP90 complexes frequently act in tandem, with the former participating in the folding of the client proteins and HSP90 stabilizing them in a way favorable for interaction with ligands. HSP90 forms complexes with an array of co-chaperones that both regulate its interaction with client proteins and stimulate its ATPase activity. By binding to different co-chaperones HSP90 acquires specificity for different families of client proteins. Many of the HSP90-client proteins are involved in tumor cell growth and HSP90 inhibitors are important as potential anticancer drugs. Inhibition of HSP90 also prevents the formation of protein aggregates in models of Parkinson disease, Huntington disease, and others. This recombinant protein may be used in conjunction with p23 (AP-170) in various in vitro protein refolding assays.
全称：Heat shock protein HSP 90-alpha (HSP90AA1)
说明书：待上传