Human TBK1 Protein, Recombinant


产品货号:PR00043HuP2
   
询价

规格    100ug

产品名称Human TBK1 Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Met309~Glu385
 
标签N-His tag
 
Uniprot链接Q9UHD2
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量12.57 kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
质量验证图:/

别称NAK, T2K, NF-kappa-B-activating kinase, Serine/threonine-protein kinase TBK1
 
背景信息TBK1, also named as tumor necrosis factor (TNF) receptor-associated factor NF-kB activator (TANK)-binding kinase 1 (TBK1), NF-kB-activating kinase (NAK), T2K, is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the ‘noncanonical IkB kinases’ (IKKs) recognized for its critical role in regulating type I IFN production (PMID: 27211305). And TBK1 is an important player in yet another critical cellular function, autophagy. 

全称Serine/threonine-protein kinase TBK1 (TBK1)
 
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