Cat IL3RA Protein, Recombinant


产品货号:PR01407FeP1
   
询价

规格    100ug

产品名称Cat IL3RA Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Lys19~Leu302
 
标签/
 
Uniprot链接/
 
表达系统E.coli
 
种属Cat
 
预测 N 端Met
 
预测分子量/
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
质量验证图/

别称/
 
背景信息IL-3R alpha. Interleukin 3 is a pleiotropic cytokine produced primarily by activated T cells or mast cells. IL‑3 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage‑committed cells. The biological effects of IL‑3 on the various cell types are mediated by the binding of IL‑3 to specific cell surface receptor complexes. The functional high‑affinity human IL‑3 receptor is a heterodimer consisting of a ligand binding  alpha  subunit and the  beta  subunit. The  alpha  subunit alone binds IL‑3 with low affinity. The  beta  subunit does not bind IL‑3 by itself but is required for the high‑affinity binding of IL‑3 to the heterodimeric receptor complex. The  beta  subunit has also been found to be a component of the high‑affinity receptor complex for IL‑5 and GM‑CSF. Both the  alpha  and the  beta  subunits are members of the cytokine receptor superfamily.

全称interleukin 3 receptor subunit alpha (IL3RA)
 
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