Human IFNA1 Protein, Recombinant
产品货号：PR00016RaM1
$ 询价
规格 100ug
产品名称：Human IFNA1 Protein, Recombinant
纯度：≥95 % as determined by SDS-PAGE
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
生物活性：/
序列起止：Cys24~Ser192
标签：N-His tag
Uniprot链接：P05011
表达系统：293F
种属：Rat
预测 N 端：Met
预测分子量：/
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件：Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
复溶：Please refer to COA for detailed information
质量验证图：/
别称：IFNA1, IFL, LeIF D, IFN, IFN-Alpha, IFNA13, IFN-A, IFNAP22, IFN-Alpha 1b, Interferon Alpha 1b, Interferon, Leukocytic, IFN, Leukocyte, Interferon alpha-D
背景信息：IFN-alpha 1. Theinterferons (IFN) are a family of cytokines with potent antiviral,antiproliferative and immunomodulatory properties, and classified based ontheir binding specificity to cell surface receptors (1). The type I IFNbind to the interferon alpha receptor (IFNAR), which consists of two subunits:IFNAR1 ( alpha -subunit) and IFNAR2 ( beta -subunit). This binding contributes toTNF-alpha induced signaling (2, 3). Both the human and mouse genome code for more than a dozen closely related IFNa subtypes and the varous IFN a share about 80% sequence homology among them (4-5). Interferon-alpha 1 (IFNA1) is asecreted, approximately 19 kDa member of the type I interferon family ofmolecules (6). Mature mouse IFN-alpha 1 shares 63% and 82% amino acid sequenceidentity with human and rat IFN-alpha 1, respectively. Low level IFN-alpha is detectedunder physiological conditions, and the production of IFNs is markedly enhancedduring virus infection (7). Althoughoriginally discovered by its capability to fight virusreplication, IFN-alpha functions as a prototypic tumorsuppressor that represses the clinical tumorigenic phenotype in somemalignancies (7).
全称：Interferon alpha-1 (IFNA1)
说明书：待上传