Human CTNNB1 Protein, Recombinant

产品货号：PR00083HuP1
   
$ 询价

规格    100ug

产品名称：Human CTNNB1 Protein, Recombinant
 
纯度：≥95 % as determined by SDS-PAGE
 
内毒素：/
 
生物活性：/
 
序列起止：Cys439~Ser675
 
标签：N-His tag
 
Uniprot链接：P35222
 
表达系统：E.coli
 
种属：Human
 
预测 N 端：Met
 
预测分子量：26.07 kDa
 
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件：Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶：Please refer to COA for detailed information
 
质量验证图：/

别称：CTNNb1, bCat, b-Cat, CTNN-B1, Catenin Beta 1, Cadherin-Associated Protein
 
背景信息：Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. 尾-Catenin was originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, 尾-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/尾-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of 尾-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222)

全称：Catenin beta-1 (CTNNB1)
 
说明书：待上传