产品名称：Human CALR Protein, Recombinant
纯度：≥95 % as determined by SDS-PAGE
内毒素：/
生物活性：/
序列起止：Glu18~Ser193
标签：N-His tag
Uniprot链接：P27797
表达系统：E.coli
种属：Human
预测 N 端：Met
预测分子量：19.36 kDa
缓冲液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件：Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
复溶：Please refer to COA for detailed information
质量验证图：/
别称：CRT, RO, SSA, CC1qR, ERp60, HACBP, grp60, CRTC, CRP55, Calregulin, Sicca Syndrome Antigen A, Autoantigen Ro, Endoplasmic reticulum resident protein 60
背景信息：CALR,also named as grp60, ERp60, HACBP, CRP55, CRTC and Calregulin, belongs to the calreticulin family. It is a molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. CALR is a ER marker. It interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. CALR interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. The MW of CALR migrates aberrantly at 55 kDa by SDS-PAGE. Some study provided that its a new possibility for CRT-mediated tumor immune prevention and treatment.
全称：Calreticulin (CALR)