Human MLKL Protein, Recombinant


产品货号:PR00139HuP1
   
询价

规格    100ug

产品名称Human MLKL Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Lys194~Phe469
 
标签N-His tag
 
Uniprot链接Q8NB16
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量30.36 kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
质量验证图:/

别称hMLKL
 
背景信息Mixed lineage kinase domain like pseudokinase (MLKL), belongs to the protein kinase superfamily, has two MW of 54 and 30 kDa. MLKL plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children.

全称Mixed lineage kinase domain-like protein (MLKL)
 
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