Human ARG1 Protein, Recombinant


产品货号:PR00180HuP1
   
询价

规格    100ug

产品名称Human ARG1 Protein, Recombinant
 
纯度≥95 % as determined by SDS-PAGE
 
内毒素/
 
生物活性/
 
序列起止Met1~Lys322
 
标签N-His tag
 
Uniprot链接P05089
 
表达系统E.coli
 
种属Human
 
预测 N 端Met
 
预测分子量35.42 kDa
 
缓冲液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
运输方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
稳定性 & 储存条件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
复溶Please refer to COA for detailed information
 
质量验证图:/

别称ARG1, Arginase I, Liver Arginase
 
背景信息Arginase 1/ARG1. Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver (1). Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Arginase is a critical regulator of nitric oxide synthesis and vascular function (2). It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer (3). In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia (4). Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia (5).

全称Arginase-1 (ARG1)
 
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