Human ARG1 Protein, Recombinant
产品货号:PR00180HuP1
$ 询价
规格 100ug
产品名称:Human ARG1 Protein, Recombinant
纯度:≥95 % as determined by SDS-PAGE
内毒素:/
生物活性:/
序列起止:Met1~Lys322
标签:N-His tag
Uniprot链接:P05089
表达系统:E.coli
种属:Human
预测 N 端:Met
预测分子量:35.42 kDa
缓冲液:20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
运输方式:This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
稳定性 & 储存条件:Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
复溶:Please refer to COA for detailed information
质量验证图:/
别称:ARG1, Arginase I, Liver Arginase
背景信息:Arginase 1/ARG1. Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver (1). Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Arginase is a critical regulator of nitric oxide synthesis and vascular function (2). It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer (3). In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia (4). Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia (5).
全称:Arginase-1 (ARG1)
说明书:待上传