Anti-β-Catenin Antibody, Recombinant Antibody

产品编号：RMAP0E7M1
   
$ 询价

规格     100ug

产品名称：Anti-β-Catenin Antibody, Recombinant Antibody
 
经验证的应用：IHC
 
交叉反应：/
 
特异性：/
 
免疫原：/
 
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来源：Recombinant Antibody
 
纯化：Protein A purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称：Beta-catenin
 
背景信息：The catenins, (alpha, beta and gamma) are cytoplasmic proteins which bind to the highly conserved tail of the E-cadherin molecule. Beta-catenin is a component of the adherens junction, a multiprotein complex which supports Ca2+ -dependent cell-to-cell contact, which in itself is critical for adhesion, signal transmission and for anchoring the actin cytoskeleton. Beta-catenin's role is as a transcription effector of the wnt-signaling pathway. Immunohistochemistry is the best way to demonstrate nuclear expression of beta-catenin and wnt-pathway activation. This aberrant expression is observed in human tumorigenesis, and especially in colorectal cancer.

全称：/
 
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