Anti-3-nitrotyrosine Antibody, Recombinant Antibody

产品编号:RPTMD2M1
   
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规格     100ug
 

产品名称Anti-3-nitrotyrosine Antibody, Recombinant Antibody
 
克隆号
 
抗体亚型IgG
 
经验证的应用WB
 
交叉反应all
 
特异性Recognizes 3-Nitrotyrosine

免疫原Nitrotyrosine
 
制备方法/
 
来源Recombinant Mouse IgG
 
纯化Protein G联合nitro-Tyr抗原多肽亲和层析纯化.
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态:Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

别称nitro-Tyr, Nitro-Tyrosine
 
背景信息Nitric oxide (NO) is implicated in carcinogenesis, chronic infection, inflammation and neurodegeneration. High levels of both superoxide and nitric oxide in tissues interact to form peroxynitrite, a potent oxidant that can modify Tyr residues in proteins to form 3-nitro-tyrosine. Tyrosine nitration of mitochondrial manganese superoxide dismutase results in loss of enzymatic activity. The nitration of p53 at Tyr residues abolishes its capacity for binding to its DNA consensus sequence.

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