Anti-TGFB1 Antibody, Mouse Monoclonal, C1

产品编号：PM00047HuM10-C1
   
$ 询价

规格     50uL  100uL  200uL   可选

产品名称：Anti-TGFB1 Antibody, Mouse Monoclonal, C1
 
克隆号：C1
 
抗体亚型：
 
经验证的应用：WB/ICC
 
交叉反应：
 
特异性：human TGFB1

免疫原：Recombinant human TGFB1 protein, fragment Ala279~Ser 390; UniprotKB: P01137
 
制备方法：Produced in rabbits immunized with human TGFB1, and purified by antigen affinity chromatography.
 
来源：Monoclonal Mouse IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
浓度：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

别称：TGF-B1, CED, DPD1, LAP, Camurati-Engelmann Disease, Latency-associated peptide
 
背景信息：Transforming Growth Factor Beta 1, 2, and 3 (TGF-beta 1, TGF-beta 2, and TGF-beta 3) are highly pleiotropic cytokines that virtually all cell types secrete. TGF-beta molecules are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial-mesenchymal transition. Targeted deletions of these genes in mice show that each TGF-beta isoform has some non-redundant functions: TGF-beta 1 is involved in hematopoiesis and endothelial differentiation; TGF-beta 2 affects development of cardiac, lung, craniofacial, limb, eye, ear, and urogenital systems; and TGF-beta 3 influences palatogenesis and pulmonary development. The full range of in vitro biological activities of TGF-beta 5 has not yet been explored. However, TGF-beta 1, TGF-beta 2, TGF-beta 3, and TGF-beta 5 have been found to be largely interchangeable in an inhibitory bioassay, and it is anticipated that TGF-beta 5 will show a spectrum of activities similar to the other TGF-beta family members. To date, the production of TGF-beta 5 has only been demonstrated in Xenopus.
 
全称：Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (TGFB1)
 
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