Anti-CASP7 Antibody, Mouse Monoclonal, C2

产品编号:PM00547HuM10-C2
   
询价

规格     50uL  100uL  200uL   可选

产品名称Anti-CASP7 Antibody, Mouse Monoclonal, C2
 
克隆号C2
 
抗体亚型
 
经验证的应用/
 
交叉反应
 
特异性human CASP7

免疫原Recombinant human CASP7 protein, fragment Ala24~Asp198; UniprotKB: P55210
 
制备方法Produced in rabbits immunized with human CASP7, and purified by antigen affinity chromatography.
 
来源Monoclonal Mouse IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
浓度Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

别称CMH1, ICE-LAP3, MCH3, Caspase 7 Apoptosis-Related Cysteine Peptidase, Cysteine Aspartate Protease 7, Cysteinyl Aspartate Specific Proteinases 7
 
背景信息Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, the 35 kDa proform is converted into a 32 kDa intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large (18 kDa) subunit and the p10 or small (11 kDa) subunit and it is present in the brain, which is up-regulated and activated after traumatic injury(PMID:15953353). Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9(PMID:9426061). The protein is involved in the activation cascade of caspases responsible for apoptosis execution.
 
全称Caspase-7 (CASP7)
 
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