Anti-PPBP Antibody, Rabbit Polyclonal

产品编号:PA00524HuA10
   
询价

规格     50uL  100uL  200uL






产品名称Anti-PPBP Antibody, Rabbit Polyclonal
 
经验证的应用IHC/IF
 
交叉反应Rat/Monkey
 
特异性human PPBP

免疫原Recombinant human PPBP protein, fragment Ser35~Asp128; UniprotKB: P02775
 
制备方法Produced in rabbits immunized with human PPBP, and purified by antigen affinity chromatography
 
来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:
 






Figure1.Western blot analysis of extracts of various cell lines  using PPBP antibody (PA00524HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution.



 
别称CXCL7, PPBP, PBP, B-TG1, CTAP-III, CTAP3, CTAPIII, LA-PF4, LDGF, MDGF, NAP2, SCYB7, TC1, TC2, TGB1, THBGB1, Pro-Platelet Basic Protein, Beta-Thromboglobulin
 
背景信息CXCL7/NAP-2. Neutrophil Activating Peptide 2 (NAP-2), Connective Tissue Activating Protein III (CTAP-III) and  beta -thrombogulin ( beta -TG), are proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR2 and to chemoattract and activate neutrophils. Although CTAP-III,  beta -TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. It has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity
 
全称Platelet basic protein (PPBP)
 
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