Anti-CDKN2A Antibody, Rabbit Polyclonal

产品编号:PA00182HuA10
   
询价

规格     50uL  100uL  200uL  可选

产品名称Anti-CDKN2A Antibody, Rabbit Polyclonal
 
经验证的应用: WB/IHC/ICC

交叉反应/
 
特异性human CDKN2A
 
免疫原Recombinant human CDKN2A protein, fragment Met1~Asp156; UniprotKB: P42771
 
制备方法Produced in rabbits immunized with human CDKN2A, and purified by antigen affinity chromatography.
 
来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称P16, ARF, CDK4I, CMM2, INK4, INK4a, MLM, MTS1, TP16, P14, P14ARF, P16INK4a, P19, Melanoma P16, Cyclin-dependent kinase 4 inhibitor A, Multiple tumor suppressor 1
 
背景信息CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins proteins were reported. Two of them named p16-INK4 and p14 are sharing 50% identity. The third one -p14(ARF) is entirely unrelated. 10883-1-AP reacts with p16 specifically. P16 plays an essential role in regulating the cell cycle, and mutations in p16 increase the risk of developing various cancers, including melanoma.
 
全称Cyclin-dependent kinase inhibitor 2A (CDKN2A)
 
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