Anti-NR1H3 Antibody, Rabbit Polyclonal

产品编号:PA00199HuA10
   
询价

规格     50uL  100uL  200uL  可选

产品名称Anti-NR1H3 Antibody, Rabbit Polyclonal
 
经验证的应用:/

交叉反应/
 
特异性human NR1H3
 
免疫原Recombinant human NR1H3 protein, fragment Met1~Glu447; UniprotKB: Q13133
 
制备方法Produced in rabbits immunized with human NR1H3, and purified by antigen affinity chromatography.
 
来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称NR1-H3, LXR-A, LXRA, RLD-1, Nuclear Receptor Subfamily 1,Group H,Member 3, Oxysterols receptor LXR-alpha

背景信息NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. Its also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.  NR1H3 exists some isoforms with MV 51 kDa and 43-45 kDa.

全称Oxysterols receptor LXR-alpha (NR1H3)
 
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