Anti-FASN Antibody, Rabbit Polyclonal
产品编号:PA00536HuA50
$ 询价
规格 50uL 100uL 200uL 可选
产品名称:Anti-FASN Antibody, Rabbit Polyclonal
经验证的应用:ICC
交叉反应:/
特异性:human FASN
免疫原:Recombinant human FASN protein, fragment Val1864~Tyr2118; UniprotKB: P49327
制备方法:Produced in rabbits immunized with human FASN, and purified by antigen affinity chromatography
来源:Polyclonal Rabbit IgG
纯化:Immunogen affinity purified
缓冲液:Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物:Unconjugated
状态:Liquid
运输方式:This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片:
Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney cancer sections labelling FASN with purified PA00536HuA50 at 10ug/ml. Heat mediated antigen retrieval was performed using EDTA buffer (pH 9.0). Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.
别称:FAS, OA519, SDR27X1, Short Chain Dehydrogenase/Reductase Family 27X,Member 1, S-acetyltransferase, 3-oxoacyl synthase, Oleoyl hydrolase, Enoyl-acyl-carrier-protein reductase
背景信息:FASN gene codes for an enzyme essential for de novo fatty acid synthesis and cellular substrate energy metabolism. Active FASN is a homodimer in which each peptide subunit has a molecular weight of 260 kDa. FASN is overexpressed in various types of cancer including glioblastomas and is a potential therapeutic target. Recently FASN has been reported to contribute to the neurogenesis since FASN mutation caused intellectual disability in mice
全称:Fatty acid synthase (FASN)
说明书:待上传