Anti-CASP7 Antibody, Rabbit Polyclonal

产品编号：PA00547HuA10
   
$ 待定

规格     50uL  100uL  200uL  可选

 产品名称：Anti-CASP7 Antibody, Rabbit Polyclonal
 
经验证的应用：WB
 
交叉反应：/
 
特异性：human CASP7
 
免疫原：Recombinant human CASP7 protein, fragment Ala24~Asp198; UniprotKB: P55210
 
制备方法：Produced in rabbits immunized with human CASP7, and purified by antigen affinity chromatography
 
来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片：


Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human cervical cancer  sections labelling CASP7 with purified PA00547HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using EDTA buffer (pH 9.0).  Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control. 







Figure2.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human tonsil  sections labelling CASP7 with purified PA00547HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using EDTA buffer (pH 9.0).  Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control. 






Figure3.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human cervical cancer   sections labelling CASP7 with purified PA00547HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using EDTA buffer (pH 9.0).  Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.



别称：CMH1, ICE-LAP3, MCH3, Caspase 7 Apoptosis-Related Cysteine Peptidase, Cysteine Aspartate Protease 7, Cysteinyl Aspartate Specific Proteinases 7
 
背景信息：Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, the 35 kDa proform is converted into a 32 kDa intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large (18 kDa) subunit and the p10 or small (11 kDa) subunit and it is present in the brain, which is up-regulated and activated after traumatic injury(PMID:15953353). Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9(PMID:9426061). The protein is involved in the activation cascade of caspases responsible for apoptosis execution
 
全称：Caspase-7 (CASP7)
 
说明书：待上传