Anti-IL16 Antibody, Rabbit Polyclonal

产品编号:PA00019HuA10
   
询价

规格     50uL  100uL  200uL

产品名称Anti-IL16 Antibody, Rabbit Polyclonal

经验证的应用WB/IHC/IF/ICC
 
交叉反应/
 
特异性human IL16
 
免疫原Recombinant human IL16 protein, fragment Ala1212~Ser1332; UniprotKB: Q14005
 
制备方法Produced in rabbits immunized with human IL16, and purified by antigen affinity chromatography.
来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称LCF, PrIL-16, Lymphocyte Chemoattractant Factor, Pro-Interleukin 16
 
背景信息IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.
 
全称Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL16)
 
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