Anti-ACACA Antibody, Rabbit Polyclonal

产品编号:PA00270HuA10
   
询价

规格     50uL  100uL  200uL  可选

说明书
产品名称Anti-ACACA Antibody, Rabbit Polyclonal
 
经验证的应用:WB/IHC/IF/ICC

交叉反应Hu
 
特异性human ACACA
 
免疫原Recombinant human ACACA protein, fragment Met1~Val621; UniprotKB: Q13085

制备方法Produced in rabbits immunized with human ACACA, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:








Figure1.Western blot analysis of extracts of various cell lines, using ACACA antibody (PA00270HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution. 







别称ACAC, ACC1, ACCA, ACAC, ACC2, ACCB, ACACB, ACACA, Acetyl CoA Carboxylase, Biotin carboxylase

背景信息ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

全称:Acetyl-CoA carboxylase 1 (ACACA)