Anti-RBP4 Antibody, Rabbit Polyclonal

产品编号:PA00654HuA10
   
询价

规格     50uL  100uL  200uL  可选

产品名称Anti-RBP4 Antibody, Rabbit Polyclonal
 
经验证的应用:WB/IHC
 
交叉反应/
 
特异性human RBP4
 
免疫原Recombinant human RBP4 protein, fragment Glu19~Leu201; UniprotKB: P02753
 
制备方法Produced in rabbits immunized with human RBP4, and purified by antigen affinity chromatography
 
来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称PRBP, RBP, Plasma retinol-binding protein, Retinol Binding Protein 4, Plasma
 
背景信息RBP4/Retinol-Binding Protein 4. Retinol (also known as vitamin A) is unstable and insoluble in the aqueous solution (1, 2). However, retinol becomes quite stable and soluble in plasma due to its tight interaction with retinol-binding protein 4 (RBP4), also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a  beta -barrel structure with a well-defined cavity. It is secreted from the liver, a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. The retinol-RBP4-TTR complex prevents the loss of RBP4 by filtration through the kidney and increases the stability of the retinol-RBP4 complex. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision
 
全称Retinol-binding protein 4 (RBP4)
 
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