Anti-FGF12 Antibody, Rabbit Polyclonal

产品编号:PA00800HuA10
   
询价

规格     50uL  100uL  200uL

产品名称Anti-FGF12 Antibody, Rabbit Polyclonal

经验证的应用WB
 
交叉反应/
 
特异性human FGF12
 
免疫原Recombinant human FGF12 protein, fragment Met1~Thr181; UniprotKB: P61328
 
制备方法Produced in rabbits immunized with human FGF12, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:



Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human  gastric carcinoma sections labelling FGF12 with purified PA00800HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using EDTA buffer (pH 9.0).  Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.



别称FGF12B, FHF1, Fibroblast Growth Factor Homologous Factor 1, Myocyte-Activating Factor
 
背景信息FGF12 is a member of the FGF family. FGF family members play important roles in embryogenesis, angiogenesis, and wound repair. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. FGF12 plays an intracellular role in the inhibition of radiation-induced apoptosis. FGF12 is expressed abundantly in developing and adult nervous systems; therefore, FGF12 was thought to be related to nervous system development and function.
 
全称Fibroblast growth factor 12 (FGF12)
 
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