Anti-GSDMD Antibody, Rabbit Polyclonal
产品编号：PA00301HuA10
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规格 50uL 100uL 200uL
产品名称：Anti-GSDMD Antibody, Rabbit Polyclonal
经验证的应用：WB/IHC/ICC
交叉反应：Hu
特异性：human GSDMD
免疫原：Recombinant human GSDMD protein, fragment Gly276~His484; UniprotKB: P57764
制备方法：Produced in rabbits immunized with human GSDMD, and purified by antigen affinity chromatography.
来源：Polyclonal Rabbit IgG
纯化：Immunogen affinity purified
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物：Unconjugated
状态：Liquid
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片：
Figure1.Western blot analysis of extracts of various cell lines and tissue, using GSDMD antibody (PA00301HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Figure2.Western blot analysis of extracts of various cell lines and tissue,THP-1 (Human monocytic leukemia monocyte) cells were differentiated into macrophage-like cells by incubation in the presence of 50ng/ul PMA for 48h. Then treated with PrgI and PA (a NAIP-NLRC4 inflammasome trigger) for 90 min whole cell lysate. using GSDMD antibody (PA00301HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
别称：GSDMDC1, DF5L, Gasdermin Domain Containing 1
背景信息：GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1尾 secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
全称：Gasdermin-D (GSDMD)
说明书：待上传
经验证的应用：WB/IHC/ICC
交叉反应：Hu
特异性：human GSDMD
免疫原：Recombinant human GSDMD protein, fragment Gly276~His484; UniprotKB: P57764
制备方法：Produced in rabbits immunized with human GSDMD, and purified by antigen affinity chromatography.
来源：Polyclonal Rabbit IgG
纯化：Immunogen affinity purified
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物：Unconjugated
状态：Liquid
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片：
Figure1.Western blot analysis of extracts of various cell lines and tissue, using GSDMD antibody (PA00301HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Figure2.Western blot analysis of extracts of various cell lines and tissue,THP-1 (Human monocytic leukemia monocyte) cells were differentiated into macrophage-like cells by incubation in the presence of 50ng/ul PMA for 48h. Then treated with PrgI and PA (a NAIP-NLRC4 inflammasome trigger) for 90 min whole cell lysate. using GSDMD antibody (PA00301HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
别称：GSDMDC1, DF5L, Gasdermin Domain Containing 1
背景信息：GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1尾 secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
全称：Gasdermin-D (GSDMD)
说明书：待上传