Anti-CCL26 Antibody, Rabbit Polyclonal

产品编号：PA00836HuA10
   
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规格     50uL  100uL  200uL

产品名称：Anti-CCL26 Antibody, Rabbit Polyclonal

经验证的应用：/
 
交叉反应：/
 
特异性：human CCL26
 
免疫原：Recombinant human CCL26 protein, fragment Ser27~Leu94; UniprotKB: Q9Y258
 
制备方法：Produced in rabbits immunized with human CCL26, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称：CCL26, SCYA26, IMAC, TSC-1, Eotaxin 3, Thymic stroma chemokine-1, Chemokine(C-C-Motif)ligand 26, Thymic Stroma Chemokine-1, Small Inducible Cytokine Subfamily A 26
 
背景信息：CCL26/Eotaxin-3. Eotaxin-3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3/CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin-3/CCL26 expression can also be detected in various tissues. The expression of Eotaxin-3/CCL26 in vascular endothelial cells has been shown to be up-regulated by IL-13 and IL-4.Eotaxin-3/CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. RecombinantEotaxin-3/CCL26 has been produced in insect cells using a baculovirus expression system and shown to contain 71 aa residues. RecombinantEotaxin-3/CCL26 is chemotactic for eosinophils and PHA-activated T cells. Eotaxin-3/CCL26 induces calcium flux in eosinophils as well as in CCR3-transfected cells. Eotaxin-3/CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands. Both the 71 aa residue and 68 aa residue variants of recombinant Eotaxin-3 have been expressed in E. coli and found to have equal potency in inducing chemotaxis of a human CCR3-transfected cell line.
 
全称：C-C motif chemokine 26 (CCL26)
 
说明书：待上传