Anti-ABCB1 Antibody, Rabbit Polyclonal

产品编号：PA00337HuA10
   
$ 询价

规格     50uL  100uL  200uL

产品名称：Anti-ABCB1 Antibody, Rabbit Polyclonal

经验证的应用：WB
 
交叉反应：/
 
特异性：human ABCB1
 
免疫原：Recombinant human ABCB1 protein, fragment Thr1023~Gln1280; UniprotKB: P08183

制备方法：Produced in rabbits immunized with human ABCB1, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片：


Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human small intestine sections labelling ABCB1 with purified PA00337HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using Heat mediated antigen retrieval using Bond™ Epitope Retrieval Solution  (EDTA, pH 9.0) . Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.



别称：CD243, ABCB1, ABC20, CLCS, GP170, MDR1, PGY1, P-Glycoprotein, Multidrug resistance protein 1, ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1, Colchicin Sensitivity
 
背景信息：ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer. For optimal WB detection with 22336-1-AP, we recommend to avoid boiling the sample after lysis.

全称：ATP-dependent translocase ABCB1 (ABCB1)
 
说明书：待上传