Anti-ME2 Antibody, Rabbit Polyclonal
产品编号:PA00844HuA10
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规格 50uL 100uL 200uL
产品名称:Anti-ME2 Antibody, Rabbit Polyclonal
经验证的应用:WB
交叉反应:/
特异性:human ME2
免疫原:Recombinant human ME2 protein, fragment Gly220~Ala426; UniprotKB: P23368
制备方法:Produced in rabbits immunized with human ME2, and purified by antigen affinity chromatography.
来源:Polyclonal Rabbit IgG
纯化:Immunogen affinity purified
缓冲液:Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物:Unconjugated
状态:Liquid
运输方式:This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片:
Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon sections labelling ME2 with purified PA00844HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using EDTA buffer (pH 9.0). Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.
别称:ODS1
背景信息:ME2(malic enzyme 2) is also named as NAD-ME and belongs to the malic enzymes family. ME1, ME2 are important for NADPH production, lipogenesis and glutamine metabolism, but ME2 has a more profound effect. ME2 is a genome-coded mitochondrial enzyme that converts malate to pyruvate and is involved in neuronal synthesis of the neurotransmitter 纬-aminobutyric acid (GABA)(PMID:15532013). This protein has 2 isoforms produced by alternative splicing with the MW of 65 kDa and 54 kDa.
全称:NAD-dependent malic enzyme, mitochondrial (ME2)
说明书:
说明书 |