Anti-MFN2 Antibody, Rabbit Polyclonal

产品编号：PA00362HuA10
   
$ 询价

规格     50uL  100uL  200uL

产品名称：Anti-MFN2 Antibody, Rabbit Polyclonal

经验证的应用：WB/IHC/IF/ICC
 
交叉反应：/
 
特异性：human MFN2
 
免疫原：Recombinant human MFN2 protein, fragment Met1~Lys316; UniprotKB: O95140

制备方法：Produced in rabbits immunized with human MFN2, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称：CMT2A, CMT2A2, CPRP1, HSG, MARF, Transmembrane GTPase MFN2
 
背景信息：MFN2, also named as CPRP1 and KIAA0214, belongs to the mitofusin family. It is an Essential transmembrane GTPase, which mediates mitochondrial fusion. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression of MFN2 induces the formation of mitochondrial networks. It plays an important role in the regulation of vascular smooth muscle cell proliferation. Defects in MFN2 are the cause of Charcot-Marie-Tooth disease type 2A2 (CMT2A2). Defects in MFN2 are the cause of Charcot-Marie-Tooth disease type 6 (CMT6). Ubiquitinated forms of Mfn2 (mono- and polyubiquitinated) are present during mitophagy.

全称：Mitofusin-2 (MFN2)
 
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