Anti-PRDX1 Antibody, Rabbit Polyclonal

产品编号：PA00903HuA10
   
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规格     50uL  100uL  200uL

产品名称：Anti-PRDX1 Antibody, Rabbit Polyclonal

经验证的应用：/
 
交叉反应：/
 
特异性：human PRDX1
 
免疫原：Recombinant human PRDX1 protein, fragment Ser2~Lys199; UniprotKB: Q06830
 
制备方法：Produced in rabbits immunized with human PRDX1, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称：MSP23, NKEFA, PAG, PAGA, PAGB, TDPX2, Natural killer cell-enhancing factor A, Proliferation-associated, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2
 
背景信息：PRDX1(Peroxiredoxin-1), also named as PAGA, PAGB, TDPX2, PAG or NKEF-A, belongs to the ahpC/TSA family. PRDX1 is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone, respectively. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2 (PMID: 9497357). It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. PRDX1 can form a dimer, and also can be phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity (PMID: 22583657, 11986303).
 
全称：Peroxiredoxin-1 (PRDX1)
 
说明书：待上传