Anti-OPA1 Antibody, Rabbit Polyclonal

产品编号：PA00382HuA10
   
$ 询价

规格     50uL  100uL  200uL

产品名称：Anti-OPA1 Antibody, Rabbit Polyclonal

经验证的应用：WB/ICC
 
交叉反应：/
 
特异性：human OPA1
 
免疫原：Recombinant human OPA1 protein, fragment Met285~Lys561; UniprotKB: O60313

制备方法：Produced in rabbits immunized with human OPA1, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称：MGM1, NPG, NTG, largeG, Dynamin-Like 120 kDa Protein, Mitochondrial, Optic atrophy protein 1
 
背景信息：OPA1 is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. OPA1 localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c.  OPA1 is associated with the inner membrane and protects cells from apoptosis by regulating inner membrane dynamics. Mutation of OPA1 causes the disease dominant optic atrophy, a degeneration of the retinal ganglion cells. OPA1 undergoes complex posttranscriptional regulation and posttranslational proteolysis. OPA1 is regulated by proteolytic cleavage, which degrades long OPA1 isoforms into short isoforms. The gene OPA1 can be cleaved into some chains with MW 100 kDa and 80-90 kDa.

全称：Dynamin-like 120 kDa protein, mitochondrial (OPA1)
 
说明书：