Anti-F3 Antibody, Rabbit Polyclonal

产品编号：PA00400HuA10
   
$ 询价

规格     50uL  100uL  200uL

产品名称：Anti-F3 Antibody, Rabbit Polyclonal

经验证的应用：WB/IHC/ICC
 
交叉反应：/
 
特异性：human F3
 
免疫原：Recombinant human F3 protein, fragment Ser33~glu251; UniprotKB: P13726

制备方法：Produced in rabbits immunized with human F3, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称：CD142, FIII, F3, TFA, Thromboplastin, Coagulation Factor III
 
背景信息：Coagulation Factor III/Tissue Factor. Coagulation Factor III/Tissue Factor (TF), also known as thromboplastin and CD142, is an integral membrane protein found in a variety of cell types. It functions as a protein cofactor/receptor of Coagulation Factor VII, which is synthesized in the liver and circulated in the plasma (1). Upon binding of TF, the inactive factor VII is rapidly converted into activated VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and has also important coagulation‑independent functions such as angiognesis (2). Synthesized as a 295 amino acid precursor, TF consists of a signal peptide (residues 1 to 32) and the mature chain (residues 33 to 295). As a type I membrane protein, it contains a transmembrane region (residues 252 to 274) and a cytoplasmic tail (residues 275 to 295) (3-6). The purified rhTF corresponds to the ectodomain (residues 34 to 251) and is potent in activating thermolysin-processed Recombinant Human Coagulation Factor VII (Catalog # 2338‑SE) under the conditions described in Activity Assay Protocol.

全称：Tissue factor (F3)

说明书：

说明书