Anti-CPT1A Antibody, Rabbit Polyclonal

产品编号:PA00431HuA10
   
询价

规格     50uL  100uL  200uL
产品名称Anti-CPT1A Antibody, Rabbit Polyclonal

经验证的应用WB
 
交叉反应Hu/Ra
 
特异性human CPT1A
 
免疫原Recombinant human CPT1A protein, fragment Pro264~Glu603; UniprotKB: P50416

制备方法Produced in rabbits immunized with human CPT1A, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:





Figure1.Western blot analysis of extracts of various cell lines  using CPT1A antibody (PA00431HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution. 







Figure2.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney sections labelling CPT1A with purified PA00431HuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using Heat mediated antigen retrieval using Bond™Epitope Retrieval Solution  (EDTA, pH 9.0) . Tissue was counterstained with Hematoxylin.Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.



别称CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform
 
背景信息CPT1A, also named as CPT1, CPT1-L and L-CPTI, belongs to the carnitine/choline acetyltransferase family. It is Localized Chromosome 11q13.1-2. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1A is an active forms of related liver-type carnitine palmitoyltransferase I.   (PMID: 11001805). CPT1A deficiency presents as recurrent attacks of fasting hypoketotic hypoglycemia. (PMID: 15363638). This antibody can bind the close sequences genes.

全称Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)

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