Anti-SMAD4 Antibody, Rabbit Polyclonal
产品编号:PA00469HuA10
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规格 50uL 100uL 200uL
产品名称:Anti-SMAD4 Antibody, Rabbit Polyclonal
经验证的应用:WB/ICC
交叉反应:/
特异性:human SMAD4
免疫原:Recombinant human SMAD4 protein, fragment Trp323~Asp552; UniprotKB: Q13485
制备方法:Produced in rabbits immunized with human SMAD4, and purified by antigen affinity chromatography.
来源:Polyclonal Rabbit IgG
纯化:Immunogen affinity purified
缓冲液:Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物:Unconjugated
状态:Liquid
运输方式:This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片:
Figure1.Western blot analysis of extracts of various cell lines using SMAD4 antibody (PA00469HuA10) at 1:1000 dilution. Lysates/proteins: 25ug per lane.Blocking buffer: 10% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 10s.
别称:DPC4, JIP, MADH4, Deletion target in pancreatic carcinoma 4
背景信息:Mammalian homologs of the Drosophila Mad gene include Smad1, Smad2, Smad3, Smad4 (DPC4), Smad5, Smad6, Smad7 and Smad8. Smad1 and Smad5 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members . Smad6 and Smad7 regulate the response to activin/ TGF signaling by interfering with TGF -mediated phosphorylation of other Smad family members. This antibody is a rabbit polyclonal antibody raised against an internal region of human SMAD4.
全称:Mothers against decapentaplegic homolog 4 (SMAD4)
说明书:待上传