Anti-SMAD4 Antibody, Rabbit Polyclonal

产品编号:PA00469HuA10
   
询价

规格     50uL  100uL  200uL

产品名称Anti-SMAD4 Antibody, Rabbit Polyclonal

经验证的应用WB/ICC
 
交叉反应/
 
特异性human SMAD4
 
免疫原Recombinant human SMAD4 protein, fragment Trp323~Asp552; UniprotKB: Q13485

制备方法Produced in rabbits immunized with human SMAD4, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:






Figure1.Western blot analysis of extracts of various cell lines  using SMAD4 antibody (PA00469HuA10) at 1:1000 dilution. Lysates/proteins: 25ug per lane.Blocking buffer: 10% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 10s.
 
 









别称DPC4, JIP, MADH4, Deletion target in pancreatic carcinoma 4
 
背景信息Mammalian homologs of the Drosophila Mad gene include Smad1, Smad2, Smad3, Smad4 (DPC4), Smad5, Smad6, Smad7 and Smad8.  Smad1 and Smad5 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF  and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members . Smad6 and Smad7 regulate the response to activin/ TGF  signaling by interfering with TGF -mediated phosphorylation of other Smad family members. This antibody is a rabbit polyclonal antibody raised against an internal region of human SMAD4.

全称Mothers against decapentaplegic homolog 4 (SMAD4)

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