Anti-H2AX Antibody, Rabbit Polyclonal
产品编号：PA00074HuA10
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规格 50uL 100uL 200uL
产品名称：Anti-H2AX Antibody, Rabbit Polyclonal
经验证的应用：WB/IHC/IF
交叉反应：/
特异性：human H2AX
免疫原：Recombinant human H2AX protein, fragment Ser2~Tyr143; UniprotKB: P16104
制备方法：Produced in rabbits immunized with human H2AX, and purified by antigen affinity chromatography.
来源：Polyclonal Rabbit IgG
纯化：Immunogen affinity purified
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物：Unconjugated
状态：Liquid
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片：
Figure1.Western blot analysis of extracts of various cell lines , using H2AFX antibody (PA00074HuA10) at 2ug/ml dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Blocking buffer: 5% nonfat dry milk in TBST.
别称：H2AX
背景信息：Histone H2A.X belongs to the histone H2A family, which is synthesized in G1 and S phase. It is involved in nucleosomal organization of chromatin together with other histone proteins, and is specially important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability. The calculated molecular weight of H2AX is 15 kDa, but the ubiquitinated H2A.X is about 22 kDa.
全称：Histone H2AX (H2AX)
说明书：待上传