Anti-RIPK1 Antibody, Rabbit Polyclonal

产品编号:PA00493HuA10
   
询价

规格     50uL  100uL  200uL
产品名称Anti-RIPK1 Antibody, Rabbit Polyclonal

经验证的应用WB/IHC/ICC
 
交叉反应Hu/Mu
 
特异性human RIPK1
 
免疫原Recombinant human RIPK1 protein, fragment Phe17~Tyr289; UniprotKB: Q13546

制备方法Produced in rabbits immunized with human RIPK1, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:






Figure1.Western blot analysis of extracts of various cell lines  using RIPK1 antibody (PA00493HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution. 






 
 







Figure2.Western blot analysis of extracts of various cell lines  using RIPK1 antibody (PA00493HuA10) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution. 


 




别称RIP, Receptor-Interacting Protein, Cell death protein RIP, Serine/threonine-protein kinase RIP
 
背景信息RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).

全称Receptor-interacting serine/threonine-protein kinase 1 (RIPK1)

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