Anti-CTNNB1 Antibody, Rabbit Polyclonal

产品编号：CP00083HuA10

$ 询价

规格     50uL  100uL  200uL

产品名称：Anti-CTNNB1 Antibody, Rabbit Polyclonal

经验证的应用：WB/IF/ICC
 
交叉反应：/
 
特异性：human CTNNB1
 
免疫原：Recombinant human CTNNB1 protein, fragment Cys439~Ser675; UniprotKB: P35222
 
制备方法：Produced in rabbits immunized with human CTNNB1, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

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别称：CTNNb1, bCat, b-Cat, CTNN-B1, Catenin Beta 1, Cadherin-Associated Protein
 
背景信息：Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. 尾-Catenin was originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, 尾-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/尾-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of 尾-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222)
 
全称：Catenin beta-1 (CTNNB1)
 
说明书：待上传