Anti-MMP9 Antibody, Rabbit Polyclonal

产品编号:PA00095HuA10
   
询价

规格     50uL  100uL  200uL

产品名称Anti-MMP9 Antibody, Rabbit Polyclonal

经验证的应用WB/IHC/IF/ICC
 
交叉反应/
 
特异性human MMP9
 
免疫原Recombinant human MMP9 protein, fragment Gly213~Ala399; UniprotKB: P14780
 
制备方法Produced in rabbits immunized with human MMP9, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
别称GELB, Gelatinase B, CLG4B, CLG4-B, 92 KDa Gelatinase, 92kDa Type IV Collagenase
 
背景信息Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP-1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 maybe be divided into five distinct domains: a pro-domain which is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a proline-rich linker region, and a carboxyl terminal hemopexin-like domain. In addition to the human enzyme, the recombinant mouse MMP-9 is also available (Catalog # 909-MM).
 
全称Matrix metalloproteinase-9 (MMP9)
 
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