Anti-MMP2 Antibody, Rabbit Polyclonal

产品编号:PA00100HuA10
   
询价

规格     50uL  100uL  200uL

产品名称Anti-MMP2 Antibody, Rabbit Polyclonal

经验证的应用WB/IHC/ICC
 
交叉反应Hu
 
特异性human MMP2
 
免疫原Recombinant human MMP2 protein, fragment Ala228~Cys660; UniprotKB: P08253
 
制备方法Produced in rabbits immunized with human MMP2, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:






Figure1.Western blot analysis of extracts of  various cell lines and tissues , using MMP2 antibody (PA00100HuA10) at 2ug/ml dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution.Blocking buffer: 5% nonfat dry milk in TBST.  





 
 











Figure1.Western blot analysis of extracts of  various cell lines and tissues , using MMP2 antibody (PA00100HuA10) at 2ug/ml dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution.Blocking buffer: 5% nonfat dry milk in TBST.  



 
 







别称CLG4, CLG4A, MMP-II, MONA, TBE-1, PEX, Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase
 
背景信息Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP‑2 (gelatinase A), a type IV collagenase, can degrade a broad range of substrates including type IV, V, VII and X collagens as well as elastin and fibronectin. It is believed to act synergistically with interstitial collagenase (MMP‑1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP‑2 has been shown to be associated with many connective tissue cells as well as neutrophils, macrophages and monocytes. Structurally, MMP‑2 may be divided into several distinct domains: a pro-domain which is cleaved upon activation; a catalytic domain containing the zinc binding site; a fibronectin-like domain thought to play a role in substrate targeting; and a carboxyl terminal (hemopexin-like) domain containing 2 N-linked glycosylation sites.
 
全称72 kDa type IV collagenase (MMP2)
 
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