Anti-MMP2 Antibody, Rabbit Polyclonal

产品编号：PA00100MuA10
   
$ 询价

规格     50uL  100uL  200uL

产品名称：Anti-MMP2 Antibody, Rabbit Polyclonal

经验证的应用：/
 
交叉反应：/
 
特异性：mouse MMP2
 
免疫原：Recombinant mouse MMP2 protein, fragment Ile34~Cys662; UniprotKB: P33434
 
制备方法：Produced in rabbits immunized with mouse MMP2, and purified by antigen affinity chromatography.

来源：Polyclonal Rabbit IgG
 
纯化：Immunogen affinity purified
 
缓冲液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物：Unconjugated
 
状态：Liquid
 
运输方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片：


Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human cervical cancer sections labelling MMP2 with purified PA00100MuA10 at 10ug/ml. Heat mediated antigen retrieval was performed using citrate buffer (pH 6.0) .  Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.





别称：CLG4, CLG4A, MMP-II, MONA, TBE-1, PEX, Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase
 
背景信息：Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP‑2 (gelatinase A), a type IV collagenase, can degrade a broad range of substrates including type IV, V, VII and X collagens as well as elastin and fibronectin. It is believed to act synergistically with interstitial collagenase (MMP‑1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP‑2 has been shown to be associated with many connective tissue cells as well as neutrophils, macrophages and monocytes. Structurally, MMP‑2 may be divided into several distinct domains: a pro-domain which is cleaved upon activation; a catalytic domain containing the zinc binding site; a fibronectin-like domain thought to play a role in substrate targeting; and a carboxyl terminal (hemopexin-like) domain containing 2 N-linked glycosylation sites.
 
全称：72 kDa type IV collagenase (MMP2)
 
说明书：待上传