Anti-CDH2 Antibody, Rabbit Polyclonal

产品编号:PA00138HuA10
   
询价

规格     50uL  100uL  200uL


说明书

产品名称Anti-CDH2 Antibody, Rabbit Polyclonal

经验证的应用WB
 
交叉反应/
 
特异性human CDH2
 
免疫原Recombinant human CDH2 protein, fragment Asp160~Phe497; UniprotKB: P19022
 
制备方法Produced in rabbits immunized with human CDH2, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:






Figure 1. Application in WB
Western blot analysis of extracts of various cell lines and tissues, using CDH2 antibody (PA00138HuA10) at 1μg/mL. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Blocking buffer: 5% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 2 s.
 
 
 

别称CDw325, CD325, CDHN, CDH2, Cadherin 2 Type 1, N-Cadherin
 
背景信息Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane glycoprotein and a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619).
 
全称Cadherin-2 (CDH2)