Anti-HDAC1 Antibody, Rabbit Polyclonal

产品编号:PA00155HuA10
   
询价

规格     50uL  100uL  200uL

产品名称Anti-HDAC1 Antibody, Rabbit Polyclonal

经验证的应用WB/IHC/IF/ICC
 
交叉反应Hu
 
特异性human HDAC1
 
免疫原Recombinant human HDAC1 protein, fragment Met1~Ala482; UniprotKB: Q13547
 
制备方法Produced in rabbits immunized with human HDAC1, and purified by antigen affinity chromatography.

来源Polyclonal Rabbit IgG
 
纯化Immunogen affinity purified
 
缓冲液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶联物Unconjugated
 
状态Liquid
 
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

图片:






Figure1.Western blot analysis of extracts of  various cell lines , using HDAC1  antibody (PA00155HuA10) at 2ug/ml dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)  at 1:10000 dilution.Blocking buffer: 5% nonfat dry milk in TBST.












别称HDAC1, GON10, HD1, RPD3, RPD3L1
 
背景信息Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex, which is responsible for gene expression silencing. It also plays an important role in the control of cell proliferation and differentiation by interacting with RB, p53 and other transcription factors. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 1 was primarily found in the nucleus. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human HDAC1. The calcualted molecular weight of HDAC1 is 55 kDa, but modified HDAC1 is about 60-65 kDa .
 
全称Histone deacetylase 1 (HDAC1)
 
说明书
说明书