Anti-HDAC1 Antibody, Rabbit Polyclonal
产品编号:PA00155HuA10
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规格 50uL 100uL 200uL
产品名称:Anti-HDAC1 Antibody, Rabbit Polyclonal
经验证的应用:WB/IHC/IF/ICC
交叉反应:Hu
特异性:human HDAC1
免疫原:Recombinant human HDAC1 protein, fragment Met1~Ala482; UniprotKB: Q13547
制备方法:Produced in rabbits immunized with human HDAC1, and purified by antigen affinity chromatography.
来源:Polyclonal Rabbit IgG
纯化:Immunogen affinity purified
缓冲液:Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶联物:Unconjugated
状态:Liquid
运输方式:This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
储存条件:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
图片:
Figure1.Western blot analysis of extracts of various cell lines , using HDAC1 antibody (PA00155HuA10) at 2ug/ml dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Blocking buffer: 5% nonfat dry milk in TBST.
别称:HDAC1, GON10, HD1, RPD3, RPD3L1
背景信息:Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex, which is responsible for gene expression silencing. It also plays an important role in the control of cell proliferation and differentiation by interacting with RB, p53 and other transcription factors. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 1 was primarily found in the nucleus. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human HDAC1. The calcualted molecular weight of HDAC1 is 55 kDa, but modified HDAC1 is about 60-65 kDa .
全称:Histone deacetylase 1 (HDAC1)
说明书:
说明书 |